Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491024 | 0.85 | POLB (0.50) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL146097 | 0.81 | ALDH1A1 (0.47) | POLBALDH1A1HPGDLTB4RLTB4R2 | |
| SCHEMBL29140671 | 0.78 | ALDH1A1 (0.46) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4257732 | 0.78 | POLB (0.50) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL145533 | 0.76 | TSHR (0.50) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27718239 | 0.75 | NPSR1 (0.44) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27986455 | 0.73 | CYP3A4 (0.49) | LMNA | |
| SCHEMBL27985499 | 0.72 | ABL1 (0.48) | POLBKDM4EHPGDLMNAMAPT | |
| SCHEMBL28413351 | 0.72 | POLB (0.44) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7193907 | 0.71 | CYP2D6 (0.57) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102458405-A | Novel anti-inflammatory agents | RESVERLOGIX CORP | 2012-05-16 | — | — | CN | disclosed |