Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 2/20 | 0.34 |
| ▸ | ADH1C | P00326 | 2/20 | 0.34 |
| ▸ | ADH1A | P07327 | 2/20 | 0.34 |
| ▸ | ADH4 | P08319 | 2/20 | 0.34 |
| ▸ | ADH7 | P40394 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27862418 | 0.91 | TSHR (0.39) | TSHRSMN1; SMN2CTSKCA2CA1 | |
| SCHEMBL27861775 | 0.90 | TSHR (0.34) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL21694545 | 0.80 | TSHR (0.50) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL18489641 | 0.80 | CYP3A4 (0.38) | TSHRSMN1; SMN2PLA2G2CCA2CA1 | |
| SCHEMBL27861734 | 0.78 | TSHR (0.41) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL19245444 | 0.77 | DNM1 (0.42) | TSHRZDHHC7PLA2G2CCA2DNM1 | |
| SCHEMBL5490012 | 0.76 | TSHR (0.38) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL27887524 | 0.75 | TSHR (0.38) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL27861771 | 0.75 | TSHR (0.42) | TSHRSMN1; SMN2CTSKCA2CA1 | |
| SCHEMBL22575823 | 0.74 | TSHR (0.48) | TSHRSMN1; SMN2ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102656194-A | Mixed donor system for high melt flow and high activity | BASF CORP | 2012-09-05 | — | — | CN | disclosed |