Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | LTK | P29376 | 1/20 | 0.30 |
| ▸ | GRK5 | P34947 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020418 | 0.81 | MAP2K1 (0.37) | MKNK2CDC25BMKNK1CHEK1DAPK3 | |
| SCHEMBL5422250 | 0.74 | MKNK2 (0.36) | MKNK2CDC25BMKNK1CHEK1DAPK3 | |
| SCHEMBL30021651 | 0.74 | MKNK2 (0.36) | MKNK2CDC25BMKNK1CHEK1DAPK3 | |
| SCHEMBL19553234 | 0.74 | DAPK3 (0.47) | MKNK2CDC25BMKNK1CHEK1DAPK3 | |
| SCHEMBL18426927 | 0.72 | CDC25B (0.33) | MKNK2CDC25B | |
| SCHEMBL6375214 | 0.72 | CDC25B (0.33) | CDC25B | |
| SCHEMBL24061564 | 0.71 | CA12 (0.43) | MKNK2MKNK1 | |
| SCHEMBL1699110 | 0.69 | CYP1A2 (0.50) | CDC25B | |
| SCHEMBL29588246 | 0.69 | CYP1A2 (0.50) | CDC25B | |
| SCHEMBL9923733 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087527-A1 | ULTRAVIOLET ABSORBERS, AND PHARMACEUTICAL COMPOSITIONS AND COSMETICS CONTAINING PYRIMIDINE COMPOUNDS FOR UV PROTECTION | AWAYA AKIRA (JP) | 2010-08-05 | — | — | WO | disclosed |