Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42288 | 1.00 | MAOB (0.42) | MAOBMAOATAAR1DPP4HTR2A | |
| SCHEMBL27889476 | 1.00 | MAOB (0.42) | MAOBMAOATAAR1DPP4HTR2A | |
| Methylamine SCHEMBL42507 | 0.96 | MAOB (0.40) | MAOBMAOATAAR1DPP4HTR2A | |
| SCHEMBL28682799 | 0.82 | MAOB (0.34) | MAOBMAOATAAR1 | |
| SCHEMBL28931899 | 0.82 | SLC6A3 (0.42) | MAOBMAOATAAR1SLC6A4SLC6A3 | |
| SCHEMBL588410 | 0.82 | SLC6A4 (0.42) | MAOBMAOATAAR1SLC6A4SLC6A3 | |
| Methylamine SCHEMBL28201991 | 0.82 | MEN1 (0.33) | MAOBMAOATAAR1DPP4 | |
| SCHEMBL28678419 | 0.82 | MEN1 (0.35) | TAAR1HTR2A | |
| SCHEMBL12466046 | 0.82 | SLC6A4 (0.42) | MAOBMAOATAAR1SLC6A4SLC6A3 | |
| SCHEMBL7453568 | 0.81 | GAA (0.34) | MAOBMAOATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101460461-B | Process for preparation of enantiomerically enriched cyclic beta-aryl or heteroaryl carboxylic acids | HOFFMANN LA ROCHE | 2012-10-03 | — | — | CN | claimed |