Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 7/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 5/20 | 0.40 |
| ▸ | SRC | P12931 | 5/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557993 | 0.84 | CSNK1D (0.47) | BACE1LCKKDRJAK3MAPK14 | |
| SCHEMBL610225 | 0.79 | EGFR (0.57) | LCKKDRJAK3MAPK14CSNK1D | |
| SCHEMBL30912753 | 0.79 | EGFR (0.57) | LCKKDRJAK3MAPK14CSNK1D | |
| SCHEMBL2632884 | 0.76 | LCK (0.57) | BACE1LCKKDRJAK3MAPK14 | |
| SCHEMBL2130969 | 0.76 | PIK3CG (0.53) | BACE1LCKKDRJAK3MAPK14 | |
| Benzene SCHEMBL28800797 | 0.76 | EGFR (0.53) | LCKKDRJAK3MAPK14CSNK1D | |
| SCHEMBL15679285 | 0.76 | LCK (0.49) | LCKKDRJAK3MAPK14CSNK1D | |
| SCHEMBL2853685 | 0.76 | KDM4E (0.46) | BACE1MAPTAXLGFERL3MBTL1 | |
| SCHEMBL446874 | 0.76 | KDM4E (0.46) | BACE1MAPTAXLGFERL3MBTL1 | |
| SCHEMBL31391518 | 0.76 | BACE1 (0.46) | BACE1MAPTAXLGFERL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102491949-A | Method for synthesizing 2-(N-alkyl) aminopyrimidine derivatives by means of N-alkylation | UNIV NANJING SCIENCE & TECH | 2012-06-13 | — | — | CN | disclosed |