Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 16/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28798345 | 0.88 | EPHA2 (0.47) | EPHA2KDREPHB4EGFR | |
| SCHEMBL28798367 | 0.87 | EPHA2 (0.50) | EPHA2KDREPHB4EGFR | |
| SCHEMBL28798422 | 0.87 | EGFR (0.48) | EPHA2KDREPHB4EGFR | |
| SCHEMBL28829750 | 0.83 | EGFR (0.46) | EPHA2KDREPHB4EGFR | |
| SCHEMBL28829760 | 0.83 | EPHA2 (0.44) | EPHA2KDREPHB4EGFR | |
| SCHEMBL28798380 | 0.82 | EPHA2 (0.50) | EPHA2KDREPHB4EGFR | |
| SCHEMBL28829777 | 0.82 | HDAC3 (0.46) | EPHA2KDREPHB4EGFR | |
| SCHEMBL28829757 | 0.82 | EGFR (0.46) | EPHA2KDREPHB4EGFR | |
| SCHEMBL28829770 | 0.81 | EGFR (0.47) | EPHA2KDREPHB4EGFR | |
| SCHEMBL28938268 | 0.81 | EPHA2 (0.44) | EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835683-A | Quinazoline-4, 6-diamine compound containing morpholinyl aromatic heterocycle and preparation method thereof | 江苏食品药品职业技术学院 | 2022-08-02 | — | — | CN | disclosed |