Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 1.00 |
| ▸ | CLK2 | P49760 | 1/20 | 0.76 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | EED | O75530 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.55 |
| ▸ | CBR1 | P16152 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377175 | 1.00 | MAOA (1.00) | MAOACLK2ESR1ESR2MEN1 | |
| Alternariol SCHEMBL29423320 | 0.87 | CLK2 (1.00) | MAOACLK2ESR1ESR2NUAK1 | |
| Alternariol SCHEMBL1096830 | 0.87 | CLK2 (1.00) | MAOACLK2ESR1ESR2NUAK1 | |
| Verrulactone A SCHEMBL29929581 | 0.81 | MAOA (0.67) | MAOACLK2ESR1ESR2MEN1 | |
| SCHEMBL30321445 | 0.80 | MAOA (0.67) | MAOACLK2ESR1ESR2MEN1 | |
| SCHEMBL31465207 | 0.80 | MAOA (0.66) | MAOACLK2ESR1ESR2MEN1 | |
| SCHEMBL30321460 | 0.78 | MEN1 (0.71) | MAOACLK2ESR1ESR2MEN1 | |
| SCHEMBL30335047 | 0.78 | MEN1 (0.71) | MAOACLK2ESR1ESR2MEN1 | |
| SCHEMBL30321458 | 0.77 | MAOA (0.63) | MAOACLK2ESR1ESR2MEN1 | |
| SCHEMBL28721629 | 0.77 | MAOA (0.62) | MAOACLK2ESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114540206-A | Method for in vitro degradation of alternariol monomethyl ether by using aspergillus oryzae PC2 intracellular enzyme | 湘潭大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-111595976-B | Method for analyzing residues of six alternaria alternata toxins in solanaceous vegetables | 上海市农业科学院 | 2022-04-01 | — | — | CN | disclosed |
| CN-111595976-A | Method for analyzing residues of six alternaria alternata toxins in solanaceous vegetables | 上海市农业科学院 | 2020-08-28 | — | — | CN | disclosed |