Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048895 | 0.83 | NOTUM (0.42) | NOTUMADRA2AADRA2BADRA2CP2RX7 | |
| SCHEMBL30109124 | 0.75 | NOTUM (0.39) | NOTUMALDH1A1SLC22A12SLC6A2SLC6A4 | |
| SCHEMBL4167876 | 0.75 | NOTUM (0.39) | NOTUMALDH1A1SLC22A12SLC6A2SLC6A4 | |
| SCHEMBL30109225 | 0.74 | KMT2A (0.42) | ALDH1A1CYP1A2TSHRRAB9AL3MBTL1 | |
| SCHEMBL2117227 | 0.74 | KMT2A (0.42) | ALDH1A1CYP1A2TSHRRAB9AL3MBTL1 | |
| SCHEMBL30711258 | 0.72 | ACLY (0.47) | NOTUMSLC22A12L3MBTL1KMT2A | |
| SCHEMBL1349273 | 0.72 | ACLY (0.47) | NOTUMSLC22A12L3MBTL1KMT2A | |
| SCHEMBL436336 | 0.71 | MEN1 (0.41) | ADRA2AADRA2BADRA2CP2RX7ALDH1A1 | |
| SCHEMBL30109166 | 0.71 | MEN1 (0.41) | ADRA2AADRA2BADRA2CP2RX7ALDH1A1 | |
| SCHEMBL7165911 | 0.71 | NPC1 (0.45) | ALDH1A1SLC6A2RAB9AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102770425-A | Indolyl-piperidinylbenzylamines as beta-tryptase inhibitors | SANOFI SA | 2012-11-07 | — | — | CN | disclosed |