Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 18/20 | 0.52 |
| ▸ | PHGDH | O43175 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800144 | 1.00 | PTGER4 (0.52) | PTGER4PHGDHPTGER2PTGER3PTGDR | |
| SCHEMBL28800166 | 0.87 | PTGER4 (0.52) | PTGER4PHGDHPTGER2 | |
| SCHEMBL28800165 | 0.87 | PTGER4 (0.52) | PTGER4PHGDHPTGER2 | |
| SCHEMBL28800160 | 0.82 | PTGER4 (0.55) | PTGER4PTGER2PTGER3PTGDR | |
| SCHEMBL28800163 | 0.82 | PTGER4 (0.55) | PTGER4PTGER2PTGER3PTGDR | |
| SCHEMBL28946338 | 0.79 | NOTUM (0.43) | — | |
| SCHEMBL28800173 | 0.79 | PTGER4 (0.52) | PTGER4PTGER2 | |
| SCHEMBL28800170 | 0.79 | PTGER4 (0.52) | PTGER4PTGER2 | |
| SCHEMBL28800158 | 0.78 | TDP1 (0.49) | PTGER4PHGDH | |
| SCHEMBL28800155 | 0.78 | TDP1 (0.49) | PTGER4PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790176-A | Imidazole compound and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-26 | — | — | CN | disclosed |