Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 7/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800158 | 1.00 | TDP1 (0.49) | TDP1NR1H4SMN1; SMN2PHGDHPTGER4 | |
| SCHEMBL28800170 | 0.91 | PTGER4 (0.52) | NR1H4SMN1; SMN2PTGER4ALDH1A1 | |
| SCHEMBL28800166 | 0.91 | PTGER4 (0.52) | NR1H4SMN1; SMN2PHGDHPTGER4ALDH1A1 | |
| SCHEMBL28800165 | 0.91 | PTGER4 (0.52) | NR1H4SMN1; SMN2PHGDHPTGER4ALDH1A1 | |
| SCHEMBL28800173 | 0.91 | PTGER4 (0.52) | NR1H4SMN1; SMN2PTGER4ALDH1A1 | |
| SCHEMBL28800169 | 0.89 | ALDH1A1 (0.49) | NR1H4PHGDHPTGER4ALDH1A1 | |
| SCHEMBL28800167 | 0.89 | ALDH1A1 (0.49) | NR1H4PHGDHPTGER4ALDH1A1 | |
| SCHEMBL28800141 | 0.89 | TDP1 (0.47) | TDP1SMN1; SMN2PHGDHALDH1A1MAPK1 | |
| SCHEMBL28800139 | 0.89 | TDP1 (0.47) | TDP1SMN1; SMN2PHGDHALDH1A1MAPK1 | |
| SCHEMBL28800160 | 0.88 | PTGER4 (0.55) | NR1H4PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790176-A | Imidazole compound and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-26 | — | — | CN | disclosed |