Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22530986 | 0.83 | KDM4E (0.52) | METTL3KDM4ETP53CSNK1DCSNK1G2 | |
| SCHEMBL15261502 | 0.82 | KDM4E (0.63) | METTL3KDM4ETP53CSNK1DCSNK1G2 | |
| SCHEMBL22499049 | 0.81 | METTL3 (0.51) | METTL3KDM4EHPGDTP53CSNK1D | |
| SCHEMBL12618991 | 0.76 | KDM4E (0.45) | METTL3KDM4EHPGDCSNK1DCSNK1G2 | |
| SCHEMBL10311331 | 0.76 | APP (0.50) | METTL3KDM4ETP53CSNK1DCSNK1G2 | |
| SCHEMBL22499286 | 0.76 | APP (0.47) | METTL3KDM4ETP53CSNK1DCSNK1G2 | |
| SCHEMBL25774521 | 0.76 | APP (0.47) | METTL3KDM4ETP53CSNK1DCSNK1G2 | |
| SCHEMBL28800287 | 0.76 | METTL3 (0.57) | METTL3KDM4EHPGDTP53ALDH1A1 | |
| SCHEMBL1733873 | 0.75 | PTGS1 (0.53) | METTL3KDM4ECSNK1DCSNK1G2APP | |
| SCHEMBL27030289 | 0.74 | METTL3 (0.58) | METTL3KDM4EHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113905787-A | METTL3 inhibiting compounds | 斯托姆治疗有限公司 | 2022-01-07 | — | — | CN | disclosed |