Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.60 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30706508 | 0.92 | ALDH1A1 (0.69) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL125431 | 0.92 | ALDH1A1 (0.69) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Hydrochloric Acid SCHEMBL27691744 | 0.90 | ALDH1A1 (0.67) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Bicarbonate SCHEMBL29556909 | 0.90 | ALDH1A1 (0.67) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Methylamine SCHEMBL28758015 | 0.87 | ALDH1A1 (0.62) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL29915528 | 0.86 | ALDH1A1 (0.71) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL1242243 | 0.86 | ALDH1A1 (0.71) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Niacin SCHEMBL30690216 | 0.85 | ALDH1A1 (0.84) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Hydrochloric Acid SCHEMBL27841975 | 0.84 | ALDH1A1 (0.68) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL9792676 | 0.84 | MKNK1 (0.64) | ALDH1A1APPGAAHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666495-A | Potassium channel modulators | ABBOTT LAB | 2012-09-12 | — | — | CN | disclosed |