Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001015 | 0.78 | HTT (0.50) | USP7HPGDLMNATSHRHTT | |
| SCHEMBL1002490 | 0.75 | USP7 (0.74) | USP7HPGDHDAC1HDAC8HDAC6 | |
| SCHEMBL27827191 | 0.72 | DRD2 (0.48) | — | |
| SCHEMBL4575757 | 0.67 | USP7 (0.57) | USP7HPGDLMNATSHRMAPT | |
| SCHEMBL4575776 | 0.66 | USP7 (0.54) | USP7HPGDHDAC1HDAC8HDAC6 | |
| SCHEMBL2270509 | 0.65 | HPGD (0.36) | USP7HPGDHDAC1HDAC8HDAC6 | |
| SCHEMBL16635790 | 0.64 | HPGD (0.49) | USP7HPGDLMNATSHRHTT | |
| SCHEMBL27903340 | 0.64 | HDAC1 (0.41) | HPGDLMNATSHRHDAC1HDAC8 | |
| SCHEMBL27903315 | 0.63 | HDAC1 (0.40) | HPGDLMNATSHRHDAC1HDAC8 | |
| SCHEMBL28254346 | 0.62 | PRCP (0.40) | PRCPCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858338-A | Pharmaceutical compositions for the treatment of pain and other indications | MERCK SHARP & DOHME | 2013-01-02 | — | — | CN | disclosed |