Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.37 |
| ▸ | CDK9 | P50750 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707692 | 0.88 | CCNT1 (0.49) | HSD11B1PTGDR2SLC6A4POLBRXFP1 | |
| SCHEMBL14739552 | 0.86 | MAPK11 (0.48) | HSD11B1PTGDR2SLC6A4CCNT1CDK9 | |
| SCHEMBL7707688 | 0.84 | HSD11B1 (0.47) | HSD11B1PTGDR2SLC6A4POLBRXFP1 | |
| SCHEMBL7712303 | 0.83 | MAPK11 (0.47) | HSD11B1PTGDR2SLC6A4HSD17B10MAPK11 | |
| SCHEMBL14739107 | 0.81 | HSD11B1 (0.48) | HSD11B1POLBCCNT1CDK9HSD17B10 | |
| SCHEMBL7711798 | 0.80 | RHEB (0.39) | HSD11B1PTGDR2SLC6A4CDK9 | |
| SCHEMBL14738750 | 0.80 | RHEB (0.39) | HSD11B1PTGDR2SLC6A4CDK9 | |
| SCHEMBL14738748 | 0.80 | RHEB (0.39) | HSD11B1PTGDR2SLC6A4CDK9 | |
| SCHEMBL14738973 | 0.77 | PDK2 (0.37) | HSD11B1PTGDR2SLC6A4MAPT | |
| SCHEMBL7712729 | 0.77 | PDK2 (0.37) | HSD11B1PTGDR2SLC6A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102917707-A | Azaindole derivatives useful as modulators of FAAH | MERCK SHARP & DOHME | 2013-02-06 | — | — | CN | disclosed |