Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27398981 | 0.91 | TSHR (0.45) | HMGB1TSHRMYCKDM4EHSD17B10 | |
| Ethylene Glycol SCHEMBL28111694 | 0.90 | TSHR (0.53) | TSHRMYCKDM4EHSD17B10ALDH1A1 | |
| Propylamine SCHEMBL27346910 | 0.88 | TSHR (0.49) | HMGB1TSHRMYCKDM4EHSD17B10 | |
| Benzene SCHEMBL28200229 | 0.88 | TSHR (0.52) | HMGB1TSHRMYCKDM4EHSD17B10 | |
| SCHEMBL28857359 | 0.86 | TSHR (0.47) | HMGB1TSHRMYCKDM4EHSD17B10 | |
| SCHEMBL28172624 | 0.86 | TSHR (0.47) | HMGB1TSHRMYCKDM4EHSD17B10 | |
| 1,3-Propanediol SCHEMBL28172486 | 0.86 | TSHR (0.50) | TSHRMYCKDM4EHSD17B10ALDH1A1 | |
| Propanol SCHEMBL27261793 | 0.86 | TSHR (0.50) | TSHRMYCKDM4EHSD17B10ALDH1A1 | |
| Alcohol SCHEMBL27709246 | 0.85 | TSHR (0.53) | HMGB1TSHRMYCKDM4EHSD17B10 | |
| Hydrazine SCHEMBL28166056 | 0.85 | TSHR (0.57) | HMGB1TSHRMYCKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102725373-B | Compositions and methods for polishing bulk silicon | CABOT MICROELECTRONICS CORP | 2015-05-06 | — | — | CN | claimed |
| CN-102725373-A | Compositions and methods for polishing bulk silicon | CABOT MICROELECTRONICS CORP | 2012-10-10 | — | — | CN | claimed |