SCHEMBL28857359

SCHEMBL28857359

Cc1c(C(=O)O)cccc1C(=O)O.NCCCCCCCCCCCCN

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
HMGB1 P09429 1/20 0.47
MYC P01106 2/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HSD17B10 Q99714 2/20 0.46
HPGD P15428 2/20 0.46
NPC1 O15118 1/20 0.44
CASP3 P42574 1/20 0.44
RAB9A P51151 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
ALOX15 P16050 1/20 0.43
ALB P02768 1/20 0.41
G6PD P11413 1/20 0.41
CASP7 P55210 1/20 0.41
CASP6 P55212 1/20 0.41
MMP2 P08253 1/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28172624 1.00 TSHR (0.47) TSHRHMGB1MYCALDH1A1KDM4E
Putrescine SCHEMBL28110610 0.95 TSHR (0.44) TSHRHMGB1MYCALDH1A1KDM4E
SCHEMBL28126374 0.93 ALDH1A1 (0.44) TSHRHMGB1ALDH1A1MEN1LMNA
Octadecylamine SCHEMBL28210994 0.93 ALDH1A1 (0.44) TSHRHMGB1ALDH1A1MEN1LMNA
Tetradecylamine SCHEMBL27874843 0.92 DNM1 (0.45) TSHRHMGB1ALDH1A1MEN1KMT2A
SCHEMBL27398981 0.89 TSHR (0.45) TSHRHMGB1MYCALDH1A1KDM4E
Diaminooctane SCHEMBL28161215 0.89 TSHR (0.40) TSHRHMGB1MYCALDH1A1KDM4E
Diaminooctane SCHEMBL28858786 0.87 TSHR (0.39) TSHRHMGB1MYCALDH1A1KDM4E
Monoethanolamine SCHEMBL28800952 0.86 HMGB1 (0.49) TSHRHMGB1MYCALDH1A1KDM4E
Propylamine SCHEMBL27346910 0.86 TSHR (0.49) TSHRHMGB1MYCALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105899586-B Polyamide-based thermoplastic elastomer composition and molded article thereof 三井化学株式会社 2018-02-13 CN disclosed