Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27822580 | 0.83 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28114837 | 0.81 | TDP1 (0.36) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28295991 | 0.79 | TDP1 (0.37) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27891068 | 0.78 | TDP1 (0.42) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27831894 | 0.78 | TDP1 (0.42) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28290478 | 0.78 | TDP1 (0.42) | TDP1 | |
| SCHEMBL2437050 | 0.78 | DRD2 (0.33) | — | |
| Tert-Butyl Formate SCHEMBL27814649 | 0.77 | TDP1 (0.48) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28325448 | 0.77 | TDP1 (0.41) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28067918 | 0.77 | TDP1 (0.41) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102939290-B | 2,3-dihydro-1H-indenes-1-base-2,7-diaza spiro [3.5] nonane derivatives and as the antagonist of growth hormone-releasing peptide acceptor or the purposes of inverse agonist | PFIZER INC. (US) | 2015-09-16 | — | — | CN | disclosed |
| CN-102939290-A | 2,3 dihydro-1h-inden-1-yl- 2,7-diazaspiro [3.6] nonane derivatives and their use as antagonists or inverse agonists of the ghrelin receptor | PFIZER | 2013-02-20 | — | — | CN | disclosed |