Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29705860 | 0.84 | HPGD (0.47) | POLBTDP1MEN1KMT2ANPC1 | |
| SCHEMBL17867572 | 0.76 | NTRK1 (0.39) | POLBL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL6987562 | 0.75 | MAPK14 (0.58) | MEN1KMT2ANPC1RAB9AMAPK14 | |
| SCHEMBL7373297 | 0.74 | POLB (0.39) | POLBL3MBTL1TDP1KMT2ACYP1A2 | |
| SCHEMBL17867588 | 0.73 | KDM4E (0.46) | POLBL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL28801139 | 0.73 | RXFP1 (0.41) | L3MBTL1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL16764938 | 0.72 | MIF (0.48) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL17967744 | 0.72 | KDM4E (0.37) | POLBL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL3265389 | 0.70 | POLB (0.44) | POLBL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL11657180 | 0.70 | PDE4B (0.49) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884050-B | Tetrahydroisoquinoline derivatives | UCB生物制药私人有限公司 | 2022-07-05 | — | — | CN | disclosed |