Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823573 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL2690420 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL2690418 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL2690423 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL2824358 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL2822554 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL2821863 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL2821347 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL31368972 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTADORA1 | |
| SCHEMBL2826984 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956945-B | Octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-01-11 | — | — | CN | disclosed |