Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | EPHB3 | P54753 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464068 | 0.89 | ATR (0.43) | BRD9NPC1RAB9AEPHB3IDO1 | |
| SCHEMBL31291214 | 0.87 | BRD9 (0.35) | BRD9EPHB3IDO1DGAT1BRD4 | |
| SCHEMBL26545672 | 0.86 | SMN1; SMN2 (0.42) | RAB9ATP53LMNAHTTMEN1 | |
| SCHEMBL25757792 | 0.86 | ATR (0.35) | BRD9EPHB3IDO1DGAT1ATR | |
| Bicarbonate SCHEMBL27034030 | 0.83 | SMN1; SMN2 (0.39) | RAB9ATP53LMNAHTTMEN1 | |
| SCHEMBL31291297 | 0.81 | SMN1; SMN2 (0.40) | RAB9ATP53LMNAHTTMEN1 | |
| SCHEMBL25757107 | 0.77 | ATR (0.42) | BRD9EPHB3IDO1DGAT1ATR | |
| SCHEMBL25757841 | 0.77 | ATR (0.35) | BRD9NPC1RAB9AEPHB3TP53 | |
| SCHEMBL17843777 | 0.76 | DRD2 (0.42) | RAB9ATP53LMNAHTTMEN1 | |
| SCHEMBL15017438 | 0.76 | SMN1; SMN2 (0.40) | RAB9ATP53LMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884050-B | Tetrahydroisoquinoline derivatives | UCB生物制药私人有限公司 | 2022-07-05 | — | — | CN | disclosed |