SCHEMBL28801293

SCHEMBL28801293

CC(C)(C)OC(=O)N1CC[C@@H](c2cccc(OCc3ccc(Cl)cc3F)n2)[C@@H](O)C1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24485813 1.00 GLP1R (0.54) GLP1R
SCHEMBL28801265 1.00 GLP1R (0.54) GLP1R
SCHEMBL20280106 1.00 GLP1R (0.54) GLP1R
SCHEMBL30662703 0.93 GLP1R (0.55) GLP1R
SCHEMBL28801287 0.93 GLP1R (0.55) GLP1R
SCHEMBL24485500 0.93 GLP1R (0.55) GLP1R
SCHEMBL20266399 0.88 GLP1R (0.58) GLP1R
SCHEMBL22320032 0.88 GLP1R (0.58) GLP1R
SCHEMBL20266472 0.88 GLP1R (0.58) GLP1R
SCHEMBL20266522 0.88 GLP1R (0.58) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250257052-A1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF PFIZER INC. (US) 2025-08-14 US disclosed
US-12319669-B2 GLP-1 receptor agonists and uses thereof PFIZER INC. (US) 2025-06-03 US disclosed
US-20240034725-A1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF PFIZER INC. (US) 2024-02-01 US disclosed
US-11802121-B2 GLP-1 receptor agonists and uses thereof PFIZER INC. (US) 2023-10-31 US disclosed
US-20230124938-A1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF PFIZER INC. (US) 2023-04-20 US disclosed
EP-3555064-B9 GLP-1 RECEPTOR AGONISTS AND USES THEREOF PFIZER (US) 2023-03-01 EP disclosed
US-11512070-B2 GLP-1 receptor agonists and uses thereof PFIZER INC. (US) 2022-11-29 US disclosed
EP-3555064-B1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF PFIZER (US) 2022-11-23 EP disclosed
CN-110325530-B GLP-1 receptor agonists and uses thereof 辉瑞大药厂 2022-01-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11512070-B2 GLP-1 receptor agonists and uses thereof GLP1R, GIPR, GPR119 GLP1R 1/4885
US-20250257052-A1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF GLP1R, GIPR, GPR119 GLP1R 1/4885
US-12319669-B2 GLP-1 receptor agonists and uses thereof GLP1R, GIPR, GPR119 GLP1R 1/4885
US-11802121-B2 GLP-1 receptor agonists and uses thereof GLP1R, GIPR, GPR119 GLP1R 1/4885
US-20240034725-A1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF GLP1R, GIPR, GPR119 GLP1R 1/4885
US-20230124938-A1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF GLP1R, GIPR, GPR119 GLP1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.