Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.54 |
| ▸ | DDR2 | Q16832 | 5/20 | 0.54 |
| ▸ | KDR | P35968 | 9/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 3/20 | 0.47 |
| ▸ | FLT3 | P36888 | 3/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.47 |
| ▸ | PLK4 | O00444 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | FYN | P06241 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | LYN | P07948 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1330644 | 0.88 | FGFR1 (0.57) | FGFR1DDR2KDRFGFR3KIT | |
| SCHEMBL1331637 | 0.88 | KDR (0.64) | FGFR1DDR2KDRKITFLT3 | |
| SCHEMBL28804742 | 0.88 | FGFR1 (0.56) | FGFR1DDR2KDRFGFR3FGFR2 | |
| SCHEMBL28804745 | 0.88 | FGFR1 (0.56) | FGFR1DDR2KDRFGFR3FGFR2 | |
| SCHEMBL1331332 | 0.86 | FGFR1 (0.71) | FGFR1DDR2KDRKITFLT3 | |
| SCHEMBL27910424 | 0.83 | FGFR1 (0.60) | FGFR1KDRFGFR3FGFR2KIT | |
| SCHEMBL27893345 | 0.81 | FGFR2 (0.55) | FGFR1KDRFGFR3FGFR2KIT | |
| SCHEMBL1331406 | 0.81 | FGFR1 (0.58) | FGFR1DDR2KDRFGFR3KIT | |
| SCHEMBL27893344 | 0.79 | FGFR2 (0.53) | FGFR1KDRFGFR3FGFR2KIT | |
| SCHEMBL1330849 | 0.78 | KDR (0.56) | FGFR1DDR2KDRFGFR3KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958927-A | Indazole Inhibitors of Kinases | ABBOTT LAB | 2013-03-06 | — | — | CN | disclosed |