Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2039555 | 0.91 | TPSAB1 (0.46) | CNR1CNR2TPSAB1HCRTR1HCRTR2 | |
| SCHEMBL12695203 | 0.89 | TPSAB1 (0.53) | CNR1CNR2TPSAB1 | |
| Hydrochloric Acid SCHEMBL12543739 | 0.88 | TPSAB1 (0.52) | CNR1CNR2TPSAB1 | |
| SCHEMBL28801378 | 0.86 | CNR1 (0.46) | CNR1CNR2TPSAB1HCRTR1HCRTR2 | |
| SCHEMBL27893694 | 0.85 | TPSAB1 (0.45) | CNR1TPSAB1 | |
| SCHEMBL27893609 | 0.83 | TPSAB1 (0.48) | CNR1TPSAB1 | |
| SCHEMBL27876894 | 0.83 | CNR1 (0.45) | CNR1CNR2TPSAB1 | |
| SCHEMBL2037618 | 0.80 | TPSAB1 (0.48) | CNR1TPSAB1 | |
| SCHEMBL12276483 | 0.79 | TPSAB1 (0.46) | CNR1TPSAB1 | |
| SCHEMBL12643116 | 0.78 | TPSAB1 (0.48) | CNR1CNR2TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102770425-A | Indolyl-piperidinylbenzylamines as beta-tryptase inhibitors | SANOFI SA | 2012-11-07 | — | — | CN | disclosed |