Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 10/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | SCN1A | P35498 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27895327 | 0.87 | MAOB (0.62) | LMNAMAOBMAPK1HRH3ALDH1A1 | |
| SCHEMBL23425648 | 0.82 | MAOB (0.70) | LMNAMAOBALDH1A1 | |
| SCHEMBL28678935 | 0.81 | MAOB (0.65) | LMNAMAOBMAPK1HRH3ALDH1A1 | |
| SCHEMBL6042793 | 0.81 | LMNA (0.53) | LMNAHRH3ALDH1A1 | |
| SCHEMBL31385612 | 0.81 | MEN1 (0.53) | MAPK1HRH3ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL21681940 | 0.81 | KDM4E (0.55) | LMNAMAPK1HRH3ALDH1A1CYP1A2 | |
| SCHEMBL27926267 | 0.80 | MAOB (0.61) | LMNAMAOBEPHX2 | |
| SCHEMBL30344157 | 0.80 | NPC1 (0.59) | LMNAALDH1A1 | |
| SCHEMBL27934406 | 0.80 | EPHX2 (0.62) | ALDH1A1EPHX2 | |
| SCHEMBL3454279 | 0.79 | HRH3 (0.47) | LMNAMAPK1HRH3ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746255-A | Compound having anti-tumor activity, and preparation method and application thereof | ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDCINE | 2012-10-24 | — | — | CN | disclosed |