SCHEMBL28801561

SCHEMBL28801561

NCc1cc(Cl)cc(N(N)C=O)c1NC(=O)c1cc(Br)cn1-c1c(Cl)cccc1Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.33
MAPK10 P53779 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27727945 0.87 GRM5 (0.31)
SCHEMBL27748973 0.84
SCHEMBL27727884 0.84 GRM5 (0.33)
SCHEMBL28801562 0.82 ALDH1A1 (0.36) MAPK8MAPK10
SCHEMBL27895779 0.81 KDM4E (0.31)
SCHEMBL27749142 0.79 MALT1 (0.31)
SCHEMBL28777089 0.78 TRPV1 (0.31)
SCHEMBL27727872 0.76 TRPV1 (0.31)
SCHEMBL27728014 0.76 PSD (0.30)
SCHEMBL28777106 0.76 MEN1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101287721-B Hydrazide compound and pesticidal use of the same SUMITOMO CO LTD 2013-03-27 CN disclosed