Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.53 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.52 |
| ▸ | SRC | P12931 | 10/20 | 0.51 |
| ▸ | GAK | O14976 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15279141 | 0.91 | EGFR (0.62) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL4743551 | 0.87 | SRC (0.51) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL28945823 | 0.86 | EGFR (0.51) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL4950543 | 0.86 | SRC (0.55) | EGFRERBB2MAP2K1SRC | |
| SCHEMBL20775350 | 0.86 | EGFR (0.51) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL4294162 | 0.83 | EGFR (0.51) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL13427130 | 0.81 | EGFR (0.53) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL4786042 | 0.81 | SRC (0.63) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL4741688 | 0.81 | MAP2K1 (0.54) | EGFRERBB2MAP2K1SRC | |
| SCHEMBL22589792 | 0.80 | SRC (0.56) | EGFRERBB2MAP2K1SRCGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012367-A | Quinoline derivative | UNIV PEKING FOUNDER GROUP CO | 2013-04-03 | — | — | CN | disclosed |
| CN-103012368-A | Quinoline derivative | UNIV PEKING FOUNDER GROUP CO | 2013-04-03 | — | — | CN | disclosed |