Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.51 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 9/20 | 0.49 |
| ▸ | GAK | O14976 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15279141 | 0.88 | EGFR (0.62) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL28801565 | 0.86 | EGFR (0.53) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL19889930 | 0.83 | SRC (0.55) | EGFRERBB2SRC | |
| SCHEMBL20775350 | 0.83 | EGFR (0.51) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL4294162 | 0.81 | EGFR (0.51) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL13427130 | 0.79 | EGFR (0.53) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL4786042 | 0.79 | SRC (0.63) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL22589792 | 0.78 | SRC (0.56) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL29363297 | 0.78 | SRC (0.56) | EGFRERBB2MAP2K1SRCGAK | |
| SCHEMBL6382288 | 0.78 | EGFR (0.55) | EGFRERBB2MAP2K1SRCGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677658-A | Bicyclic aromatic compounds and their use | 江苏开元药业有限公司 | 2023-02-03 | — | — | CN | disclosed |