Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807589 | 0.90 | MKNK1 (0.39) | OPRM1CACNA2D1USP30ATMKDM4E | |
| SCHEMBL2875006 | 0.88 | NR1I2 (0.42) | OPRM1CACNA2D1USP30ATMKDM4E | |
| SCHEMBL2874221 | 0.88 | KDM4E (0.37) | OPRM1USP30ATMKDM4EHTT | |
| SCHEMBL2870829 | 0.88 | OPRM1 (0.36) | OPRM1USP30ATMKDM4EHTT | |
| SCHEMBL2873363 | 0.87 | GAA (0.35) | OPRM1USP30ATMKDM4EHTT | |
| SCHEMBL2877284 | 0.87 | OPRM1 (0.41) | OPRM1KCNH2NR1I2CHRM2CHRM3 | |
| SCHEMBL3809138 | 0.86 | OPRM1 (0.38) | OPRM1ATMKDM4EHTTMEN1 | |
| SCHEMBL2877206 | 0.86 | KDM4E (0.38) | OPRM1USP30ATMKDM4EHTT | |
| SCHEMBL2874240 | 0.86 | KDM4E (0.38) | OPRM1USP30ATMKDM4EHTT | |
| SCHEMBL2874208 | 0.86 | KDM4E (0.38) | OPRM1USP30ATMKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |