1,2-Dichlorobenzene

1,2-Dichlorobenzene

SCHEMBL28801680

CCCCCCCCCCCCCCCCCC[SiH3].Clc1ccccc1Cl

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
KDM4E B2RXH2 1/20 0.45
TSHR P16473 2/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.38
LIPG Q9Y5X9 1/20 0.37
KCNH2 Q12809 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP2D6 P10635 1/20 0.36
DNM1 Q05193 1/20 0.36
CYP19A1 P11511 3/20 0.36
DRD3 P35462 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nonane SCHEMBL10388422 0.89 TSHR (0.56) LMNAKDM4ETSHRMEN1KMT2A
Dodecane SCHEMBL28192322 0.89 TSHR (0.56) LMNAKDM4ETSHRMEN1KMT2A
Undecane SCHEMBL27492416 0.89 TSHR (0.56) LMNAKDM4ETSHRMEN1KMT2A
1,2-Dichlorobenzene SCHEMBL7513099 0.89 TSHR (0.56) LMNAKDM4ETSHRMEN1KMT2A
Biphenyl SCHEMBL10583603 0.80 MEN1 (0.43) LMNAKDM4ETSHRMEN1KMT2A
Biphenyl SCHEMBL28529890 0.80 MEN1 (0.43) LMNAKDM4ETSHRMEN1KMT2A
Toluene SCHEMBL28392617 0.78 LMNA (0.48) LMNATSHRMEN1KMT2ATP53
1,2-Dichlorobenzene SCHEMBL7821653 0.78 LMNA (0.56) LMNAKDM4ETSHRMEN1KMT2A
1,2-Dichlorobenzene SCHEMBL27912052 0.77 TSHR (0.55) LMNAKDM4ETSHRMEN1KMT2A
Heptane SCHEMBL4432527 0.76 LMNA (0.50) LMNAKDM4ETSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102775273-A Bifurcate alkyl chain and preparation and application thereof in organic conjugated molecules UNIV BEIJING 2012-11-14 CN disclosed