SCHEMBL2880175

SCHEMBL2880175

CC1C(=O)CC(=O)CC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2692336 0.79
SCHEMBL19283814 0.74 MAPT (0.32) MAPTKDM4EALDH1A1POLBTSHR
SCHEMBL5911724 0.74 MAPT (0.32) MAPTKDM4EALDH1A1POLBTSHR
SCHEMBL28327785 0.74 MAPT (0.32) MAPTKDM4EALDH1A1POLBTSHR
SCHEMBL11834684 0.71 TRIM24 (0.36) ALDH1A1
SCHEMBL13859055 0.70 MAPT (0.33) MAPTKDM4EALDH1A1POLBTSHR
SCHEMBL10367738 0.70 KDM4E (0.31) MAPTKDM4E
SCHEMBL5911742 0.67 MAPT (0.31) MAPTKDM4EALDH1A1POLBTSHR
SCHEMBL5380269 0.67 ALDH1A1 (0.35) MAPTKDM4EALDH1A1POLBTSHR
SCHEMBL13877936 0.67 MAPT (0.43) MAPTKDM4EALDH1A1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219515-A Preparation method of oseltamivir and phosphate thereof 浙江华海药业股份有限公司 2024-12-31 CN disclosed
WO-2010111299-A2 SYNTHETIC ANTIBODIES THE ARIZONA BOARD OF REGENTS A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2010-09-30 WO disclosed
US-7223795-B2 Modified peptide derivatives and methods of use thereof CYCLACEL LIMITED (GB) 2007-05-29 US disclosed
US-7223795-B2 Modified peptide derivatives and methods of use thereof CYCLACEL LIMITED (GB) 2007-05-29 US disclosed