Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11186239 | 0.89 | MEN1 (0.61) | MEN1KMT2AATMNPC1LMNA | |
| SCHEMBL27898276 | 0.76 | PDE5A (0.40) | NPC1NPSR1RAB9ALMNAGRM5 | |
| SCHEMBL29018052 | 0.73 | MEN1 (0.68) | MEN1KMT2AATMNPC1LMNA | |
| SCHEMBL5119400 | 0.71 | PTGS2 (0.51) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL7695527 | 0.71 | NPC1 (0.40) | MEN1KMT2AATMNPC1LMNA | |
| SCHEMBL8295470 | 0.70 | CA1 (0.54) | NPC1NPSR1RAB9AALDH1A1CA1 | |
| SCHEMBL27542583 | 0.69 | MAOB (0.42) | MEN1KMT2AATMMAOAMAOB | |
| SCHEMBL9953363 | 0.69 | KMT2A (0.40) | MEN1KMT2AATMNPC1LMNA | |
| SCHEMBL6617867 | 0.69 | CYP1A2 (0.39) | MEN1KMT2AATMLMNAMAOB | |
| SCHEMBL6499602 | 0.68 | MEN1 (0.51) | MEN1KMT2AATMNPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746343-A | Chiral bis-imidazoline pincer rhodium compound, preparation and asymmetric catalysis application thereof | UNIV ZHENGZHOU | 2012-10-24 | — | — | CN | disclosed |