Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | GPR4 | P46093 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.47 |
| ▸ | HRH2 | P25021 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 3/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19479118 | 0.86 | DRD3 (0.70) | DRD3DRD2KCNA5HRH2HRH1 | |
| SCHEMBL20423457 | 0.86 | DRD3 (0.55) | DRD3EPHX2GPR4DRD2GPR119 | |
| SCHEMBL14453585 | 0.86 | KCNA5 (0.62) | DRD3EPHX2GPR4DRD2KCNA5 | |
| SCHEMBL6034847 | 0.85 | HRH2 (0.61) | DRD3EPHX2GPR4DRD2GPR119 | |
| SCHEMBL1730771 | 0.85 | HRH2 (0.58) | DRD3EPHX2GPR4DRD2GPR119 | |
| SCHEMBL23301374 | 0.85 | DRD3 (0.54) | DRD3EPHX2GPR4DRD2GPR119 | |
| SCHEMBL14453658 | 0.85 | DRD3 (0.54) | DRD3EPHX2GPR4DRD2GPR119 | |
| SCHEMBL18135536 | 0.85 | KCNA5 (0.64) | DRD3EPHX2DRD2KCNA5ALDH1A1 | |
| SCHEMBL25747712 | 0.84 | GPR4 (0.56) | DRD3EPHX2GPR4DRD2GPR119 | |
| SCHEMBL14453657 | 0.83 | DRD3 (0.52) | DRD3EPHX2GPR4DRD2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702439-A | Naphthylurea-piperazine compounds and preparation method and application thereof | 河南省锐达医药科技有限公司 | 2022-07-05 | — | — | CN | disclosed |