SCHEMBL28802012

SCHEMBL28802012

NC(C(F)(F)F)S(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA9 Q16790 2/20 0.35
CA7 P43166 2/20 0.33
CA13 Q8N1Q1 1/20 0.33
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 2/20 0.32
NT5E P21589 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28457180 0.73 CA1 (0.33) CA1CA2CA9CA7TSHR
SCHEMBL28801981 0.71 CA1 (0.32) CA1CA2CA9CA7TSHR
SCHEMBL29603096 0.71 CA1 (0.32) CA1CA2CA9CA7TSHR
SCHEMBL718983 0.69 TSHR (0.35) CA1CA2CA9CA7CA13
SCHEMBL26112006 0.69 ALDH1A1 (0.31) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL31070433 0.67 DPP4 (0.31)
SCHEMBL321210 0.67 ALDH1A1 (0.33) CA1CA2CA9ALDH1A1L3MBTL1
SCHEMBL11842579 0.67 ALDH1A1 (0.33) CA1CA2CA9ALDH1A1L3MBTL1
SCHEMBL13241631 0.67 ALDH1A1 (0.33) CA1CA2CA9ALDH1A1L3MBTL1
SCHEMBL757434 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853797-A Preparation method of alpha-amino boron cyclic compound 中山大学 2022-08-05 CN disclosed