Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | OXGR1 | Q96P68 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27899754 | 0.76 | ALDH1A1 (0.40) | KDM4EMEN1KMT2AALDH1A1PDE10A | |
| SCHEMBL27334270 | 0.76 | CYSLTR1 (0.50) | MEN1KMT2AALDH1A1PDE10ATP53 | |
| SCHEMBL4823229 | 0.73 | ALDH1A1 (0.48) | KDM4ELMNAMEN1KMT2ASUCNR1 | |
| SCHEMBL27489217 | 0.73 | ALDH1A1 (0.67) | KMT2AALDH1A1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL3275331 | 0.72 | KDM4E (0.50) | KDM4ELMNAMEN1KMT2ASUCNR1 | |
| SCHEMBL2009161 | 0.72 | CCR1 (0.48) | KDM4ELMNAMEN1KMT2ASUCNR1 | |
| SCHEMBL19952703 | 0.72 | ALDH1A1 (0.47) | KDM4ELMNAMEN1KMT2ASUCNR1 | |
| SCHEMBL7514147 | 0.72 | ALDH1A1 (0.47) | KDM4ELMNAMEN1KMT2ASUCNR1 | |
| Hydrochloric Acid SCHEMBL7450279 | 0.71 | KDM4E (0.42) | KDM4ELMNAMEN1KMT2ASUCNR1 | |
| SCHEMBL514723 | 0.71 | SUCNR1 (0.43) | KDM4ELMNAMEN1KMT2ASUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103038229-B | Heteroaryl compounds and methods of use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2016-05-11 | — | — | CN | disclosed |
| CN-103038229-A | Heteroaryl compounds and methods of use thereof | SUNOVION PHARMACEUTICALS INC | 2013-04-10 | — | — | CN | disclosed |