Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965817 | 0.88 | CA1 (0.39) | CA1CA2CA7KMT2ALMNA | |
| SCHEMBL31733944 | 0.84 | NOS1 (0.37) | KMT2ALMNAMEN1GAAAAK1 | |
| SCHEMBL11385756 | 0.84 | KMT2A (0.35) | CA1CA2CA7KMT2ALMNA | |
| SCHEMBL7814662 | 0.84 | NOS1 (0.37) | KMT2ALMNAMEN1GAAAAK1 | |
| SCHEMBL2767833 | 0.83 | KMT2A (0.34) | CA1CA2CA7KMT2ALMNA | |
| SCHEMBL7371670 | 0.82 | KMT2A (0.36) | CA1CA2CA7KMT2ALMNA | |
| SCHEMBL27656864 | 0.80 | KMT2A (0.39) | KMT2ALMNAMEN1GAAAAK1 | |
| SCHEMBL4106257 | 0.80 | KMT2A (0.39) | KMT2ALMNAMEN1GAAAAK1 | |
| SCHEMBL1066621 | 0.80 | KMT2A (0.39) | KMT2ALMNAMEN1GAAAAK1 | |
| SCHEMBL2141977 | 0.79 | NOS1 (0.38) | KMT2ALMNAMEN1GAAAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102822175-A | 5, 5-fused arylene or heteroarylene hepatitis C virus inhibitors | IDENIX PHARMACEUTICALS INC (US) | 2012-12-12 | — | — | CN | disclosed |