Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 7/20 | 0.42 |
| ▸ | HTR2C | P28335 | 7/20 | 0.42 |
| ▸ | HTR2B | P41595 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15051927 | 0.81 | NPY5R (0.46) | CYP3A4CYP2D6KDM4EALDH1A1MAPT | |
| SCHEMBL458101 | 0.81 | KDM4E (0.45) | CYP3A4CYP2D6KDM4EALDH1A1MAPT | |
| SCHEMBL27900548 | 0.80 | CNR2 (0.39) | KDM4EALDH1A1MAPTMAPK1HTT | |
| SCHEMBL458637 | 0.80 | MAPT (0.53) | KDM4EALDH1A1MAPTMAPK1HTT | |
| SCHEMBL457743 | 0.79 | PTPN1 (0.44) | KDM4EALDH1A1MAPTMAPK1HTT | |
| SCHEMBL458406 | 0.79 | KDM4E (0.45) | CYP3A4CYP2D6KDM4EALDH1A1MAPT | |
| SCHEMBL15051079 | 0.79 | KDM4E (0.46) | CYP3A4CYP2D6KDM4EALDH1A1MAPT | |
| SCHEMBL459476 | 0.78 | NPY5R (0.44) | KDM4EALDH1A1MAPTMAPK1HTT | |
| SCHEMBL460190 | 0.76 | FAAH (0.56) | ALDH1A1MAPT | |
| SCHEMBL460257 | 0.75 | NPC1 (0.64) | KDM4EALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103080086-B | Prostaglandin D synthase inhibitory piperidine compounds | TAIHO PHARMACEUTICAL CO LTD | 2014-11-05 | — | — | CN | claimed |
| CN-103080086-B | Prostaglandin D synthase inhibitory piperidine compounds | TAIHO PHARMACEUTICAL CO LTD | 2014-11-05 | — | — | CN | disclosed |
| CN-103080086-A | Prostaglandin D synthase inhibitory piperidine compounds | TAIHO PHARMACEUTICAL CO LTD | 2013-05-01 | — | — | CN | disclosed |