SCHEMBL28802414

SCHEMBL28802414

O=[N+]([O-])c1ccccc1/C=C/c1cccc2c1[nH]c1ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.52
RAB9A P51151 3/20 0.52
PARP1 P09874 1/20 0.50
MAPT P10636 2/20 0.48
SOS1 Q07889 1/20 0.46
KMT2A Q03164 4/20 0.45
CYP19A1 P11511 2/20 0.45
MEN1 O00255 2/20 0.45
TDP1 Q9NUW8 2/20 0.44
SIRT2 Q8IXJ6 1/20 0.44
MAOB P27338 1/20 0.44
IDO1 P14902 2/20 0.44
ALDH1A1 P00352 1/20 0.44
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30455197 0.84 PARP1 (0.68) NPC1PARP1MAPTKMT2ATDP1
SCHEMBL1135541 0.84 PARP1 (0.68) NPC1PARP1MAPTKMT2ATDP1
SCHEMBL27943756 0.84 KIF11 (0.57) NPC1RAB9APARP1MAPTKMT2A
SCHEMBL26164139 0.83 PARP1 (0.71) NPC1PARP1MAPTKMT2ATDP1
SCHEMBL7117038 0.80 GLA (0.59) NPC1RAB9AMAPTKMT2AMEN1
SCHEMBL10865710 0.80 GLA (0.59) NPC1RAB9AMAPTKMT2AMEN1
SCHEMBL28627821 0.79 KMT2A (0.55) NPC1PARP1MAPTKMT2ATDP1
SCHEMBL9978289 0.79 MAPT (0.69) NPC1RAB9AMAPTSOS1KMT2A
SCHEMBL14935499 0.79 MAPT (0.69) NPC1RAB9AMAPTSOS1KMT2A
SCHEMBL11049170 0.79 MAPT (0.69) NPC1RAB9AMAPTSOS1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805796-B Two-dimensional strong fluorescence polyaniline material with metal ion detection performance and preparation method thereof 武汉大学 2023-08-22 CN disclosed
CN-114805796-A Two-dimensional strong-fluorescence polyaniline material with metal ion detection performance and preparation method thereof 武汉大学 2022-07-29 CN disclosed