Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL484670 | 0.87 | LMNA (0.49) | LMNASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL10561912 | 0.83 | CA12 (0.46) | LMNASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL27859776 | 0.83 | HDAC1 (0.46) | LMNASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL4996201 | 0.82 | LMNA (0.50) | LMNASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL5256415 | 0.82 | LMNA (0.50) | LMNASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL5256419 | 0.82 | LMNA (0.50) | LMNASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL27704257 | 0.81 | CA12 (0.44) | LMNASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL19731335 | 0.81 | LMNA (0.49) | LMNASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL19879735 | 0.81 | LMNA (0.49) | LMNASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL26622086 | 0.81 | LMNA (0.47) | LMNASMN1; SMN2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097354-A | Substituted benzamide compounds | GRUENENTHAL CHEMIE | 2013-05-08 | — | — | CN | disclosed |