Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CFD | P00746 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28803202 | 1.00 | HDAC8 (0.44) | HDAC8TSHRHPGDSMN1; SMN2MAPT | |
| SCHEMBL28803327 | 0.86 | TSHR (0.41) | HDAC8TSHRHPGDSMN1; SMN2MAPT | |
| SCHEMBL19208384 | 0.85 | HDAC8 (0.57) | HDAC8HPGDSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL19208389 | 0.85 | HDAC8 (0.57) | HDAC8HPGDSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28803370 | 0.84 | CFD (0.44) | CFDALDH1A1P2RX7 | |
| SCHEMBL28803369 | 0.84 | CFD (0.44) | CFDALDH1A1P2RX7 | |
| SCHEMBL28803298 | 0.83 | CFD (0.48) | TSHRCFDALDH1A1P2RX7NPC1 | |
| SCHEMBL28803299 | 0.83 | CFD (0.48) | TSHRCFDALDH1A1P2RX7NPC1 | |
| SCHEMBL28803389 | 0.81 | CFD (0.44) | TSHRCFDALDH1A1P2RX7 | |
| SCHEMBL28803203 | 0.81 | CFD (0.46) | TSHRHPGDCFDALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490751-A | Factor D inhibitors | 拜奥克里斯特制药公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-109121414-B | Benzopyrazole compounds and analogs thereof | 拜奥克里斯特制药公司 | 2022-07-05 | — | — | CN | disclosed |