Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CFD | P00746 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28803343 | 1.00 | TSHR (0.53) | TSHRCFDCYP3A4CYP2C19P2RX7 | |
| SCHEMBL28803389 | 0.88 | CFD (0.44) | TSHRCFDP2RX7ALDH1A1CD38 | |
| SCHEMBL28803388 | 0.88 | CFD (0.44) | TSHRCFDP2RX7ALDH1A1CD38 | |
| SCHEMBL28803278 | 0.86 | CFD (0.43) | TSHRCFDP2RX7ALDH1A1CD38 | |
| SCHEMBL28803279 | 0.86 | CFD (0.43) | TSHRCFDP2RX7ALDH1A1CD38 | |
| SCHEMBL28803298 | 0.84 | CFD (0.48) | TSHRCFDP2RX7ALDH1A1CD38 | |
| SCHEMBL28803299 | 0.84 | CFD (0.48) | TSHRCFDP2RX7ALDH1A1CD38 | |
| SCHEMBL28803203 | 0.84 | CFD (0.46) | TSHRCFDP2RX7ALDH1A1CD38 | |
| SCHEMBL28803205 | 0.84 | CFD (0.46) | TSHRCFDP2RX7ALDH1A1CD38 | |
| SCHEMBL19208602 | 0.83 | TSHR (0.56) | TSHRCFDCYP3A4CYP2C19P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490751-A | Factor D inhibitors | 拜奥克里斯特制药公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-109121414-B | Benzopyrazole compounds and analogs thereof | 拜奥克里斯特制药公司 | 2022-07-05 | — | — | CN | disclosed |