Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991107 | 0.93 | PARP10 (0.65) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL725405 | 0.83 | PARP10 (0.77) | PARP10KMT2AMEN1MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL16050040 | 0.81 | PARP10 (0.74) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL9663679 | 0.81 | PARP10 (0.81) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL28803602 | 0.81 | PARP10 (0.59) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL28292356 | 0.81 | PARP10 (0.59) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL27888188 | 0.81 | SRC (0.62) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL27991110 | 0.79 | SRC (0.60) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL8205435 | 0.79 | PARP10 (0.78) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL31888 | 0.79 | PARP10 (0.70) | PARP10KMT2AMEN1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102869671-B | Degradable photocrosslinkers | 苏尔莫迪克斯公司 | 2019-04-16 | — | — | CN | claimed |
| CN-104185661-B | The lubricity medical treatment device coating of low microgranule | 苏尔莫迪克斯公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-102869671-A | Degradable photocrosslinkers | SURMODICS INC | 2013-01-09 | — | — | CN | disclosed |