SCHEMBL28804101

SCHEMBL28804101

CCN(NC)c1cccc(C(=O)O)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
ACMSD Q8TDX5 1/20 0.48
LMNA P02545 2/20 0.44
BRD4 O60885 1/20 0.37
ECE1 P42892 1/20 0.37
CYP1A2 P05177 1/20 0.37
GNE Q9Y223 1/20 0.36
ALDH1A1 P00352 2/20 0.35
P2RX7 Q99572 1/20 0.35
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
RECQL P46063 1/20 0.35
RAB9A P51151 1/20 0.35
MCL1 Q07820 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7492564 0.80 KDM4E (0.55) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL19065189 0.79 KDM4E (0.53) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL5317855 0.78 KDM4E (0.61) KDM4ETDP1ALOX15TSHRACMSD
Dipicolinic Acid SCHEMBL6882250 0.72 KDM4E (0.77) KDM4ETDP1ALOX15TSHRACMSD
Dipicolinic Acid SCHEMBL28185610 0.72 KDM4E (0.77) KDM4ETDP1ALOX15TSHRACMSD
Dipicolinic Acid SCHEMBL27876291 0.71 KDM4E (0.68) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL28973338 0.70 KDM4E (0.61) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL2638747 0.70 KDM4E (0.50) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL2641612 0.70 KDM4E (0.50) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL28628270 0.69 KDM4E (0.59) KDM4ETDP1ALOX15TSHRACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114845742-A Modified GRPR antagonist peptides for cancer imaging and treatment 慕尼黑工业大学 2022-08-02 CN disclosed