Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15652380 | 0.82 | PIM1 (0.43) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL19065189 | 0.82 | KDM4E (0.53) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL18246722 | 0.79 | MAPT (0.49) | KDM4ETDP1TSHRLMNAALDH1A1 | |
| SCHEMBL7492564 | 0.79 | KDM4E (0.55) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL2641612 | 0.79 | KDM4E (0.50) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL2638747 | 0.79 | KDM4E (0.50) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL18246600 | 0.78 | P2RX7 (0.62) | KDM4ETDP1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL28804101 | 0.78 | KDM4E (0.48) | KDM4ETDP1ALOX15TSHRACMSD | |
| Dipicolinic Acid SCHEMBL720696 | 0.78 | KDM4E (1.00) | KDM4ETDP1ALOX15TSHRACMSD | |
| Dipicolinic Acid SCHEMBL34595 | 0.78 | KDM4E (1.00) | KDM4ETDP1ALOX15TSHRACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-1332942-C | Sulfonylamino-acetic acid derivatives and their use as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-22 | — | — | CN | disclosed |
| WO-2007078184-A1 | METALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) | 2007-07-12 | — | — | WO | disclosed |
| CN-1703397-A | Sulfonylamino-acetic acid derivatives and their use as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD (CH) | 2005-11-30 | — | — | CN | disclosed |