Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 19/20 | 0.90 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.90 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.90 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.90 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valsartan SCHEMBL29518879 | 0.94 | AGTR1 (1.00) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| Valsartan SCHEMBL8476946 | 0.94 | AGTR1 (1.00) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| Valsartan SCHEMBL678231 | 0.94 | AGTR1 (1.00) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| Valsartan SCHEMBL678796 | 0.94 | AGTR1 (1.00) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| Valsartan SCHEMBL24722321 | 0.94 | AGTR1 (1.00) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| Valsartan SCHEMBL31532957 | 0.94 | AGTR1 (0.98) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL24224465 | 0.91 | AGTR1 (0.80) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| Valsartan SCHEMBL1828137 | 0.88 | AGTR1 (0.86) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL24224463 | 0.87 | AGTR1 (0.87) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL16482977 | 0.87 | AGTR1 (0.86) | AGTR1LTB4R2ABCB11GP6AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114814060-A | Detection method of valsartan amlodipine tablet related substances | 上海博志研新药物技术有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114814060-B | Detection method of valsartan amlodipine tablet related substances | 上海博志研新药物研究有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-114814060-A | Detection method of valsartan amlodipine tablet related substances | 上海博志研新药物技术有限公司 | 2022-07-29 | — | — | CN | disclosed |