SCHEMBL28804323

SCHEMBL28804323

CCCCc1ccccc1-c1ccc(-c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.49
DPP4 P27487 1/20 0.48
HSD11B1 P28845 1/20 0.44
PTGER1 P34995 1/20 0.44
PTGER4 P35408 1/20 0.44
PTGER3 P43115 1/20 0.44
PTGER2 P43116 1/20 0.44
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
LTB4R2 Q9NPC1 1/20 0.43
LIPG Q9Y5X9 1/20 0.42
KMT2A Q03164 1/20 0.42
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12610868 1.00 PPARA (0.49) PPARADPP4HSD11B1PTGER1PTGER4
SCHEMBL15391163 1.00 PPARA (0.49) PPARADPP4HSD11B1PTGER1PTGER4
SCHEMBL367335 0.96 DPP4 (0.52) PPARADPP4HSD11B1PTGER1PTGER4
SCHEMBL9812624 0.94 PPARA (0.54) PPARADPP4HSD11B1PTGER1PTGER4
SCHEMBL30784962 0.94 PPARA (0.54) PPARADPP4HSD11B1PTGER1PTGER4
Ethane SCHEMBL1275986 0.94 DPP4 (0.50) PPARADPP4HSD11B1PTGER1PTGER4
SCHEMBL27424929 0.94 DPP4 (0.50) PPARADPP4HSD11B1PTGER1PTGER4
Phosphine SCHEMBL27550721 0.94 DPP4 (0.50) PPARADPP4HSD11B1PTGER1PTGER4
SCHEMBL28825457 0.94 DPP4 (0.50) PPARADPP4HSD11B1PTGER1PTGER4
SCHEMBL10429728 0.93 PPARA (0.53) PPARADPP4HSD11B1LIPGNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105492519-A Illuminating devices with color stable thermoplastic light-transmitting articles SABIC INNOVATIVE PLASTICS IP BV 2016-04-13 CN disclosed
CN-105408408-A Color stable thermoplastic composition SABIC INNOVATIVE PLASTICS IP 2016-03-16 CN disclosed
CN-104540889-A Transparent plastic article SABIC INNOVATIVE PLASTICS IP 2015-04-22 CN disclosed
CN-103740080-A Thermoplastic polycarbonate compositions, articles made therefrom and method of manufacture SABIC INNOVATIVE PLASTICS IP 2014-04-23 CN disclosed
CN-101421323-B Loaded latex optical molecular imaging probes CARESTREAM HEALTH INC 2013-03-13 CN disclosed