Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415706 | 0.85 | CA12 (0.59) | ALDH1A1MEN1KMT2AHTTALOX5 | |
| SCHEMBL545919 | 0.83 | MEN1 (0.46) | ALDH1A1MEN1KMT2AHTTALOX5 | |
| SCHEMBL3187719 | 0.83 | MEN1 (0.46) | ALDH1A1MEN1KMT2AHTTALOX5 | |
| SCHEMBL432482 | 0.82 | MEN1 (0.66) | ALDH1A1MEN1KMT2AHTTALOX5 | |
| SCHEMBL416748 | 0.82 | MAPT (0.56) | ALDH1A1MEN1KMT2AHTTALOX5 | |
| SCHEMBL20839505 | 0.82 | MEN1 (0.48) | ALDH1A1MEN1KMT2AHTTALOX5 | |
| SCHEMBL212724 | 0.81 | ALOX5 (0.64) | ALDH1A1MEN1KMT2AALOX5MAPT | |
| SCHEMBL16397645 | 0.81 | ALOX5 (0.64) | ALDH1A1MEN1KMT2AALOX5MAPT | |
| SCHEMBL31538745 | 0.80 | ALOX5 (0.57) | ALDH1A1MEN1KMT2AHTTALOX5 | |
| Hydrochloric Acid SCHEMBL23532714 | 0.79 | ALOX5 (0.62) | ALDH1A1MEN1KMT2AALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103200936-B | Novel N-hydroxybenzamide compounds for the treatment of cancer | HOFFMANN LA ROCHE | 2015-03-11 | — | — | CN | disclosed |
| CN-103200936-A | Novel N-hydroxybenzamide compounds for the treatment of cancer | HOFFMANN LA ROCHE | 2013-07-10 | — | — | CN | disclosed |