Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL28557971 | 0.74 | DGKA (0.62) | DGKACYP3A4ALDH1A1 | |
| SCHEMBL3228372 | 0.74 | DGKA (0.62) | TDP1DGKAFAAH | |
| SCHEMBL473563 | 0.74 | TDP1 (0.64) | TDP1DGKA | |
| SCHEMBL5350282 | 0.73 | DGKA (0.66) | DGKAFAAH | |
| SCHEMBL5357954 | 0.73 | DGKA (0.66) | DGKAFAAH | |
| SCHEMBL3230032 | 0.73 | DGKA (0.66) | DGKAFAAH | |
| SCHEMBL10766992 | 0.73 | DGKA (0.66) | TDP1DGKAMEN1KMT2A | |
| SCHEMBL13431000 | 0.73 | DGKA (0.66) | DGKAFAAH | |
| SCHEMBL5352197 | 0.73 | DGKA (0.66) | DGKAFAAH | |
| SCHEMBL8663024 | 0.73 | DGKA (0.66) | TDP1DGKAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003262-A | Nitrogenated aromatic heterocyclic ring derivative | KYOWA HAKKO KIRIN CO LTD | 2013-03-27 | — | — | CN | disclosed |