Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876477 | 0.81 | KDM4E (0.61) | MAPTKDM4EGPBAR1 | |
| SCHEMBL877275 | 0.81 | KDM4E (0.54) | MAPTKDM4EGPBAR1CYP1A2CYP2C9 | |
| SCHEMBL876600 | 0.79 | KDM4E (0.57) | MAPTKDM4EGPBAR1CYP1A2CYP2C9 | |
| SCHEMBL877251 | 0.77 | KDM4E (0.75) | MAPTKDM4EGPBAR1CYP1A2CYP2C9 | |
| SCHEMBL877302 | 0.77 | KDM4E (0.58) | MAPTKDM4EGPBAR1CYP1A2CYP2C9 | |
| SCHEMBL876596 | 0.77 | KDM4E (0.58) | MAPTKDM4EGPBAR1CYP1A2CYP2C9 | |
| SCHEMBL876883 | 0.77 | MAPT (0.79) | MAPTKDM4EGPBAR1ABCB1CYP1A2 | |
| SCHEMBL15057528 | 0.76 | MAPT (0.68) | MAPTKDM4EGPBAR1CYP1A2CYP2C9 | |
| SCHEMBL876906 | 0.75 | KDM4E (0.64) | MAPTKDM4EGPBAR1CYP1A2CYP2C9 | |
| SCHEMBL876054 | 0.74 | KDM4E (1.00) | MAPTKDM4EGPBAR1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097358-B | Pharmaceutical composition | EISAI R&D MAN CO LTD | 2015-04-08 | — | — | CN | disclosed |
| CN-103097358-A | Pharmaceutical composition | EISAI R&D MAN CO LTD | 2013-05-08 | — | — | CN | disclosed |