SCHEMBL877251

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL876883	0.88	MAPT (0.79)	KDM4EMAPTCYP1A2CYP2C19CYP3A4
	SCHEMBL13242957	0.86	KDM4E (0.75)	KDM4EMAPTCYP1A2CYP2C19CYP3A4
	SCHEMBL876054	0.86	KDM4E (1.00)	KDM4EMAPTCYP1A2CYP2C19CYP3A4
	SCHEMBL875886	0.85	KDM4E (0.70)	KDM4EMAPTCYP1A2CYP2C19CYP3A4
	SCHEMBL876223	0.85	KDM4E (0.70)	KDM4EMAPTCYP1A2CYP2C19CYP3A4
	SCHEMBL876663	0.84	KDM4E (0.61)	KDM4EMAPTCYP1A2CYP2C19CYP3A4
	SCHEMBL876600	0.81	KDM4E (0.57)	KDM4EMAPTCYP1A2CYP2C19CYP3A4
	SCHEMBL26416585	0.81	KDM4E (0.64)	KDM4EMAPTCYP1A2CYP2C19CYP3A4
	SCHEMBL876508	0.80	MAPT (0.67)	KDM4EMAPTCYP1A2CYP2C19CYP3A4
	SCHEMBL877203	0.80	MAPT (0.74)	KDM4EMAPTCYP1A2CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.