Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 19/20 | 1.00 |
| ▸ | PIK3CD | O00329 | 18/20 | 1.00 |
| ▸ | EGFR | P00533 | 18/20 | 1.00 |
| ▸ | HCK | P08631 | 18/20 | 1.00 |
| ▸ | SRC | P12931 | 18/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 18/20 | 1.00 |
| ▸ | PIK3CB | P42338 | 18/20 | 1.00 |
| ▸ | MTOR | P42345 | 18/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 18/20 | 1.00 |
| ▸ | EPHB4 | P54760 | 18/20 | 1.00 |
| ▸ | PRKDC | P78527 | 18/20 | 1.00 |
| ▸ | KDR | P35968 | 17/20 | 1.00 |
| ▸ | PI4KB | Q9UBF8 | 16/20 | 1.00 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.57 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.57 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30387348 | 1.00 | ABL1 (1.00) | ABL1PIK3CDEGFRHCKSRC | |
| SCHEMBL23917199 | 0.83 | PIK3CD (0.75) | ABL1PIK3CDEGFRHCKSRC | |
| SCHEMBL30387301 | 0.82 | SRC (1.00) | ABL1PIK3CDEGFRHCKSRC | |
| SCHEMBL18258369 | 0.80 | MTOR (0.72) | ABL1PIK3CDEGFRHCKSRC | |
| SCHEMBL234181 | 0.79 | SRC (0.80) | ABL1PIK3CDEGFRHCKSRC | |
| SCHEMBL29780889 | 0.78 | SRC (0.64) | ABL1PIK3CDEGFRHCKSRC | |
| SCHEMBL21467054 | 0.78 | ABL1 (0.64) | ABL1PIK3CDEGFRHCKSRC | |
| SCHEMBL29999077 | 0.77 | PIK3CD (0.62) | ABL1PIK3CDEGFRHCKSRC | |
| SCHEMBL24096755 | 0.77 | PIK3CD (0.62) | ABL1PIK3CDEGFRHCKSRC | |
| SCHEMBL16702036 | 0.77 | EGFR (0.64) | ABL1PIK3CDEGFRHCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101506211-B | Kinase antagonists | UNIV CALIFORNIA | 2013-05-22 | — | — | CN | disclosed |